IGV Web Tool

IGV Web Tool enables researchers to explore genomic data visually, compare samples, and validate variants without local installation.

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About This Tool

IGV Web Tool renders aligned reads, variants, and annotation tracks in a browser. Users load BAM/CRAM, VCF, BED/BigWig data for a chosen genome build and region. It supports multi-track views, coordinate-based queries, and client-side caching for smooth exploration. Conceptually, data are streamed or opened from local files, decoded, and visualized as coverage bars, read layouts, and variant markers. The tool emphasizes rapid inspection, reproducibility, and easy sharing of views across researchers. Unique value comes from browser-native operation, support for remote data sources, and lightweight export options for figures or configurations. Core features include: (1) coordinate navigation, (2) multi-track rendering, (3) basic filtering by quality or allele, (4) local and remote data access, (5) per-track configuration and color-coding, (6) export of current view to JSON or image, and (7) region-based queries for quick checks across samples. Use cases include QC checks on sequencing runs, variant validation in a genomic interval, and preparing visuals for reports or publications. The tool is designed for researchers, clinicians, and data managers who need a fast, install-free visualization experience with data privacy preserved in the browser. Performance is optimized for moderate data sizes and streaming segments from remote servers when supported.

How to Use

  1. Provide inputs: select genome build and data sources (BAM/VCF/BED/BigWig) and region.
  2. Load files via URL or local upload.
  3. Explore coordinates, add or remove tracks, adjust visualization options.
  4. Run quick filters or comparisons across samples.
  5. Export the current view as JSON or image for sharing.
How to use igv web tool

Frequently Asked Questions

Find Quick Answers

What formats are supported?
Supported formats include BAM/CRAM for alignments, VCF for variants, BED and BigWig for tracks, with support for remote HTTP/HTTPS data sources and local file loading where browser capacity allows.
Can I use it offline?
The tool runs in the browser and does not require a server for basic viewing; however, loading remote datasets requires internet access and large datasets may not be feasible offline.
Is data privacy preserved?
Data loaded into the tool stays in the client memory and is not transmitted to servers by default; exporting or sharing views explicitly exports or shares data.
How do I compare multiple samples?
Add multiple data tracks for each sample, align to the same genomic region, and adjust per-track color-coding. The platform supports simultaneous visualization and region-based comparisons.

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