Down Syndrome Risk Calculator

Calculate Down syndrome risk during pregnancy using established medical parameters.

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About This Tool

This Down Syndrome Risk Calculator helps assess the probability of trisomy 21 during pregnancy using the combined test method. It considers maternal age, gestational age, nuchal translucency measurement, and serum markers (PAPP-A and β-hCG) to provide an accurate risk estimate. The tool follows established medical algorithms and includes interpretation guidelines to help understand the results. All calculations are performed client-side for privacy and speed.

How to Use

  1. Enter maternal age in years
  2. Enter gestational age in weeks
  3. Input nuchal translucency (NT) measurement in millimeters
  4. Provide serum marker values (PAPP-A in mIU/mL and β-hCG in ng/mL)
  5. Click 'Calculate Risk' to get instant results
  6. Review the calculated risk ratio and interpretation
How to use calculator down syndrome risk

Frequently Asked Questions

Find Quick Answers

What medical algorithm does this calculator use?
The calculator uses the combined test algorithm, which incorporates maternal age, gestational age, nuchal translucency measurement, and serum markers (PAPP-A and β-hCG) to estimate Down syndrome risk.
Is my data stored or sent to a server?
No, all calculations are performed entirely in your browser. No data is transmitted to any server, ensuring complete privacy.
What do the risk results mean?
Results are presented as a ratio (e.g., 1:250). A lower second number indicates higher risk. The tool also provides interpretation guidelines based on standard medical thresholds.
Can this calculator diagnose Down syndrome?
No, this is a screening tool only. It estimates probability but cannot diagnose. Always consult with a healthcare professional for definitive testing and diagnosis.

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