Kilowatt-Force Energy Calculator

Calculate kidney failure risk using the validated 8-variable Kidney Failure Risk Equation (KFRE)

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About This Tool

The KFRE (Kidney Failure Risk Equation) calculator is a validated clinical tool that estimates the 2-year and 5-year risk of progressing to kidney failure (end-stage renal disease) in patients with chronic kidney disease. This tool uses eight clinical variables including age, sex, estimated glomerular filtration rate (eGFR), albumin-to-creatinine ratio (ACR), serum albumin, serum bicarbonate, serum calcium, and serum phosphate. The results provide personalized risk estimates to help guide clinical decision-making and patient counseling.

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How to Use

Enter the patient's age in years
Select biological sex (male/female)
Input the latest eGFR value (mL/min/
73m²)
Enter the urine albumin-to-creatinine ratio (ACR) in mg/g
Provide serum albumin level (g/dL)
Enter serum bicarbonate level (mmol/L)
Input serum calcium level (mg/dL)
Provide serum phosphate level (mg/dL)
Click 'Calculate KFRE Risk' to see the 2-year and 5-year kidney failure risk percentages and risk category

Frequently Asked Questions

Find Quick Answers

What is the KFRE calculator used for?

The Kidney Failure Risk Equation (KFRE) is a validated clinical tool that estimates the risk of progressing to kidney failure (end-stage renal disease) within 2 and 5 years for patients with chronic kidney disease. It helps clinicians and patients understand prognosis and guide treatment decisions.

What do the KFRE risk categories mean?

Low risk (<5% 5-year risk): Unlikely to progress to kidney failure soon. Moderate risk (5-15% 5-year risk): Moderate chance of progression. High risk (15-30% 5-year risk): Significant risk of progression. Very high risk (>30% 5-year risk): Very likely to progress to kidney failure.

Is this calculator suitable for all patients?

The KFRE is validated for adults (age ≥18) with chronic kidney disease stages 3-5 (eGFR <60 mL/min/1.73m²). It may not be accurate for patients with acute kidney injury, kidney transplant recipients, or those receiving dialysis.

What units should I use for the lab values?

Use standard clinical units: eGFR in mL/min/1.73m², ACR in mg/g, albumin in g/dL, bicarbonate in mmol/L, calcium in mg/dL, and phosphate in mg/dL. The calculator will handle the conversions internally.

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